Added: Jacilyn Bilger - Date: 29.11.2021 18:36 - Views: 31921 - Clicks: 9552
To drug-free urine specimens, we added the following drugs of abuse to give concentrations twice the cutoff value for positive test : norcarboxy-deltatetrahydrocannabinol 9-carboxy-THCoxazepam, secobarbital, morphine, benzoylecgonine, amphetamine, or phencyclidine PCP. Visine was then added. Although measured concentrations of several drugs were decreased in the presence of Visine, false-negative were obtained only for 9-carboxy-THC for the EMIT-d.
Visine also decreased 9-carboxy-THC as measured by the Abuscreen assay. At low concentrations of Visine, false-negative cannabinoid were attributable to the benzalkonium chloride ingredient of Visine. The added Visine was not detectable by routine urine analysis and had no effect on the activity of the glucosephosphate dehydrogenase-drug conjugate used in the EMIT-d. However, Visine did increase the adhesion of 9-carboxy-THC to the borosilicate glass specimen containers.
of ultrafiltration studies with Visine suggest that 9-carboxy-THC partitions between the aqueous solvent and the hydrophobic interior Visine for drug test benzalkonium chloride micelles, thereby reducing the availability of 9-carboxy-THC in antibody-based assays.
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of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Cite Display options Display options. Abstract To drug-free urine specimens, we added the following drugs of abuse to give concentrations twice the cutoff value for positive test : norcarboxy-deltatetrahydrocannabinol 9-carboxy-THCoxazepam, secobarbital, morphine, benzoylecgonine, amphetamine, or phencyclidine PCP. Similar articles Determination of five abused drugs in nitrite-adulterated urine by immunoassays and gas chromatography-mass spectrometry. Tsai SC, et al.
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Huestis MA, et al. Investigation of nitrite adulteration on the immunoassay and GC-MS analysis of cannabinoids in urine specimens. Tsai LS, et al. Confirmatory tests for drugs in the workplace by gas chromatography-mass spectrometry. Goldberger BA, et al. J Chromatogr A. PMID: Review. Detection time of drugs of abuse in urine. Vandevenne M, et al. Acta Clin Belg. See all similar articles. Cited by 4 articles Immunoassays for drug screening in urine : Chances, challenges, and pitfalls. Forensic Sci Med Pathol. A case of psychosis after use of a detoxification kit and a review of techniques, risks, and regulations associated with the subversion of urine drug tests.
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Gov't Actions. False Negative Reactions Actions. Gas Chromatography-Mass Spectrometry Actions. Humans Actions. Nasal Decongestants Actions. Ultrafiltration Actions. Substances Benzalkonium Compounds Actions. Cannabinoids Actions. Imidazoles Actions. Secobarbital Actions. Oxazepam Actions. Morphine Actions. Dronabinol Actions. Amphetamine Actions. Cocaine Actions. Phencyclidine Actions. Copy Download.Visine for drug test
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